Telling an app to use a particular NIC

Let's say there are two PCs where each has two NICs: NIC1 and NIC2. The NIC1
on both machines are connected to the same switch. These NICs are used for
Internet access. However, what if I want to use NIC2 on both machine as the
one to transfer lots of data continuously like in a data backup situation?
Can I tell an automatic backup program to use the "backdoor" NIC2 to
transfer the data and not the NIC1? I am pretty sure there is a registry
hack where I can tell a network aware program to associate itself to one NIC
and not the other.

Network cards are cheap these days. there is no reason nowadays not to have
multihomed PCs in a LAN to maximize data traffic instead of having one NIC
taking the full load of a multitudes of programs that use the network.


.

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