Constant "Page cannot be found message"

I have Windows XP (Service Pack 2) and have IE 6.0.2900.2180. Some time ago
I had all sorts of spyware problems and I switched to Firefox and downloaded
several spyware programs. I primarily use firefox as my browser but
occasionally would use IE, and all was working fine. Recently when I try to
open IE all I get is "Page cannot be found" with the detail listing of
things to try, none of which work. I've tried looking online to
troubleshoot but I have no idea where to begin. I was hoping to just
uninstall and reinstall IE but I guess that isn't possible.



Any suggestions as to how I might get IE working again.



Thanks



Tom



PS My Firefox browser works fine, it's just Internet Explorer that I can't
get to work.


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