Folder wont delete...help?

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On my harddrive I have an empty folder and when I try to delete it I get the
message:

"Cannot read from the source file or disk"

If i double click on it to view the content it give an error message:
".....refers to a location that is unavailable....:

I have rebooted with no change.

The folder was created by a Creative application for MP3 audio. All the
applications are close.

How can I delete this unused folder?

thanks


.

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