Can't get rid of this trojan/virus

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From: John (john_at_nospam.infovis.co.uk)
Date: 06/27/04 

Date: Sun, 27 Jun 2004 14:31:52 +0100

Hi Yahya,

I've been passed a computer which had various viruses and Trojans on it.
The owner failed to update his antivirus software.

Trend, Norton and McAfee found the virues, and various adware/spyware
programs have found registry and infected files. I've carried out various
instructions on how to remove entries in the registry etc but in this
instance whatever I do a file called okinr.dll comes back to the Windows
directory and the web browser is reset to read
res://okinr.dll/index.html~10213.

Any ideas apart from formatting the disk!

Regards

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