Win 2K Adv Server and SQL Server 2K

We just brought a Dual Opteron server with 4GB RAM in to production.
As the day goes on the Server get slower in some parts of our MAS500
SQL program. When I reboot the system it takes so long for the reboot
process that I just 'reset' the machine (30+ minutes). After the
screen 'Saving your settings' it goes to the blue screen and sits there
with the hard drives showing activity (the 4 hard drives are set at
RAID 10). If I start the server in safe mode it reboots and shutsdown
fine. Other than loading Windows the only things I changed is in
Performance Options: Set for Background services. Virtual memory is
set to 2 GB. Startup and recovery options are '/fastdetect /PAE'.
Debugging info is Small memory dump. Our support from Sage software
and Systemax PC says it's Windows........

Help!!!

.

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