VB 2005 Express: Replacing parameters in a text file with TextBox values

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I have a text file with parameters like the following embedded in the text:

@@TextBox1@@, @@TextBox2@@, etc.

I know how to read this text file. However, I am trying to figure out how
to replace these parameters in the text file with values of the textboxes on
my Windows Form called Form1. For example, replace @@TextBox1@@ with value
of TextBox1, replace @@TextBox2@@ with value of TextBox2, replace
@@ComboBox1@@ with value of ComboBox1, and so on. I am told this is doable
but I am not quite sure how.

I'd appreciate any pointers.

Thanks,
J.S.

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